This site is intended for patients in Great Britain (England, Scotland and Wales) who have been prescribed PIQRAY®▼ (alpelisib) + fulvestrant.

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Useful resources for you

On this page you will find a range of materials designed to give you all the information you need to know about your treatment and how to live well with advanced breast cancer.

Downloadable resources

Click on the materials below to download them and use at your leisure. All of these documents are for GB patients only.

Tips for living
with aBC

Four steps to take care of your emotional needs

Tips to manage cancer-related fatigue

Six tips to help
manage anxiety

Read the Piqray® patient brochure for detailed information about treating your aBC with Piqray® and fulvestrant

Watch the Learning About Piqray and Hyperglycaemia video

Watch the How to Take
Piqray video


Below are some terms you might wish to become familiar with.

Advanced/metastatic breast cancer: Cancer that started in your breast but has now moved to other parts of your body.1,2

Hormone receptor-positive (HR+): Cancer cells that use hormones like oestrogen or progesterone to grow.2

Human epidermal growth factor receptor 2-negative (HER2-): Cancer cells with normal amounts and types of HER2, a protein that can cause breast cancer cells to grow and spread.3

PIK3CA mutation: Cancer cells with a change (or mutation) in a certain part of the DNA known as the PIK3CA gene. This mutation may cause cancer cells to grow and spread.4

Postmenopausal: After menopause, when a woman has not menstruated for 12 consecutive months.5,6

Progression: When cancer grows or gets worse.7 It is common for advanced breast cancer to progress after some time even if it is being treated.1 If this happens while being treated, this is sometimes called becoming resistant to that treatment.8

Targeted therapy: A type of treatment that uses drugs to target specific genes and proteins that are involved in the growth and survival of cancer cells.1,9

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Need support? Get a wealth of information on receiving support during this difficult time 

Where would you like to go next? 


aBC, advanced breast cancer.


  1. Macmillan Cancer Support. Secondary breast cancer. Available at: [Accessed November 2021].
  2. Breast cancer - Metastatic: Introduction. Available at: [Accessed November 2021].
  3. verywellhealth. HER2 positive vs. HER2 negative breast cancer. Available at: [Accessed November 2021].
  4. MedlinePlus. PI3KCA gene. Available at: [Accessed November 2021].
  5. National Cancer Institute. Definition of postmenopausal. Available at: [Accessed November 2021].
  6. NHS. Postmenopausal bleeding. Available at: [Accessed November 2021].
  7. National Cancer Institute. Definition of progression. Available at: [Accessed: November 2021].
  8. National Cancer Institute. Why do cancer treatments stop working? Overcoming treatment resistance. Available at: [Accessed November 2021].
  9. National Cancer Institute. Targeted cancer therapies. Available at: [Accessed November 2021].

▼This medicine is subject to additional monitoring. This will allow quick identification of new safety information. You can help by reporting any side effects you may get. See for how to report side effects.

UK | January 2022 | 147276