This site is intended for patients in Great Britain (England, Scotland and Wales) who have been prescribed PIQRAY®▼ (alpelisib) + fulvestrant.
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Some people experience side effects from their treatment for advanced breast cancer. Find out the most common side effects that people taking Piqray experience
Learn more >
Some people develop hyperglycaemia as a side effect of taking Piqray. Find out more about this side effect and what action you should take
Find out more about hyperglycaemia >Hyperglycaemia
(high blood sugar)
Diarrhoea
Mouth sores
Rash
Hair loss
Nausea,vomiting
Decreased appetite
Fatigue
Abnormal blood tests
Weight loss
Up to 4 out of 5 people will develop hyperglycaemia (high blood sugar) as a side effect of taking their Piqray®.2
Hyperglycaemia occurs when the level of glucose (sugar) in the blood is higher than it should be and can become serious if not managed.
Your blood sugar levels will be tested regularly before you start treatment, during treatment and after you stop treatment with Piqray + fulvestrant.1
If you develop hyperglycaemia when taking PIQRAY® + fulvestrant, your doctor may prescribe you an antidiabetic treatment and/or you may require a change to your Piqray dose temporarily, or permanently.1
Severe hyperglycaemia (high blood sugar) is considered serious, particularly if accompanied by symptoms such as confusion, dry mouth, dry or flushed skin, nausea, vomiting, tiredness, need to pass urine frequently, thirst. These could be symptoms of hyperglycaemic hyperosmolar nonketotic syndrome (HHNKS). Contact your healthcare team immediately if you have any of these symptoms1
Follow your doctor’s instructions for monitoring your blood glucose, and any changes to the dose of your medicine(s)
Make lifestyle changes, such as keeping to a healthy weight, eating a balanced diet and being more physically active3
Your doctor may prescribe a medicine or a combination of medicines to help control your blood sugar. They may also recommend interrupting or reducing your dose of Piqray, or in some cases, stopping the treatment altogether1
View the brochure and treatment tracker for help with taking alpelisib + fulvestrant
